This is pretty darn crazy. With a simple program from http://crazytalk.reallusion.com/ you can actually make any photo talk. It's a little creepy because it doesn't completely match up, so the person can look a little devilish, but it's a great thing for making your photos move and for bringing them to life.
Oh, and with a slight misspelling, http://carzytalk.reallusion.com/ you can actually make your Skype Avatar talk too.
More from the CrazyTalk Web site
Create and control a virtual cast of live talking characters ready to deliver an animated vocal performance for your video, web, mobile or messaging projects. Just a single photograph, recorded or imported audio, combined with transitional effects, animated illustrations and expressive emoticons, and CrazyTalk's powerful facial morphing animation technology is all you need to begin creating speaking actors, virtual guides, and digital hosts adding perfect personalities to any multimedia experience.